We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
GLOBETECH PUBLISHING LLC

Download Mobile App




DEXA Reveals Diabetic Boys Have Lower Bone Density

By MedImaging International staff writers
Posted on 04 Aug 2021
Print article
DEXA scans reveal T1DM affects bone density more in boys (Photo courtesy of Pixabay)
DEXA scans reveal T1DM affects bone density more in boys (Photo courtesy of Pixabay)
A new radiographic study suggests that gender may be a risk factor for osteoporosis in children and adolescents with type 1 diabetes (T1DM).

Researchers at Mahidol University (Bangkok, Thailand) conducted a study to compare bone mineral density (BMD) in 100 youths (44 boys and 56 girls; mean age 14.5 years) with T1DM, as well as in 100 healthy controls. BMD was assessed in the lumbar (L2–L4) area, the femoral neck, total hip, and total body using dual-energy x-ray absorptiometry (DEXA) scans. Metabolites in blood, including hemoglobin A1c (HbA1c), 25-hydroxyvitamin D, and inflammatory cytokines were also measured.

The results showed that total body, lumbar, and femoral neck BMD scores were lower in diabetic children than in the healthy controls. T1DM boys also had significantly lower lumbar and femoral neck BMD scores than boys in the control group, but no such differences were found between diabetic and control girls. IL-13 was positively correlated with BMD in the total cohort and among girls. In boys, IL-2 and 25-hydroxyvitamin D were positively associated with BMD, and duration of diabetes was found to negatively affect BMD. The study was published on July 10, 2021, in Bone.

“Our findings revealed BMD deficit in our diabetic cohort to be gender specific. Only boys had decreased BMD at almost all sites, while no bone deficit was found in diabetic girls,” concluded lead author pediatric endocrinologist Jeerunda Santiprabhob, MD, and colleagues. “The deleterious effect of T1DM on BMD is gender specific. The longer the duration of T1DM, the greater the deficit in BMD found among boys with T1DM.”

T1DM, also known as insulin dependent diabetes, is characterized by a loss of β-cells in the islets of Langerhans of the pancreas. The primary function of a β-cell is release insulin in response to spikes in blood glucose concentrations, while simultaneously producing more. T1DM is believed to be caused by an autoimmune response where the body destroys 70-80% of β-cells, leaving only 20–30% of them as functioning cells. This can cause the patient to experience hyperglycemia, which leads to other adverse short-term and long-term conditions.

Related Links:

Mahidol University

Gold Member
Solid State Kv/Dose Multi-Sensor
AGMS-DM+
Laptop Ultrasound Scanner
PL-3018
Advanced Cardiac MRI Analysis Software
3Di Cardiac MR
New
Thyroid Shield
Standard Thyroid Shield

Print article

Channels

Ultrasound

view channel
Image: Structure of the proposed transparent ultrasound transducer and its optical transmittance (Photo courtesy of POSTECH)

Ultrasensitive Broadband Transparent Ultrasound Transducer Enhances Medical Diagnosis

The ultrasound-photoacoustic dual-modal imaging system combines molecular imaging contrast with ultrasound imaging. It can display molecular and structural details inside the body in real time without... Read more

Nuclear Medicine

view channel
Image: PET/CT of a 60-year-old male patient with clinical suspicion of lung cancer (Photo courtesy of EJNMMI Physics)

Early 30-Minute Dynamic FDG-PET Acquisition Could Halve Lung Scan Times

F-18 FDG-PET scans are a way to look inside the body using a special dye, and these scans can be either static or dynamic. Static scans happen 60 minutes after the dye is administered into the body, showing... Read more

Imaging IT

view channel
Image: The new Medical Imaging Suite makes healthcare imaging data more accessible, interoperable and useful (Photo courtesy of Google Cloud)

New Google Cloud Medical Imaging Suite Makes Imaging Healthcare Data More Accessible

Medical imaging is a critical tool used to diagnose patients, and there are billions of medical images scanned globally each year. Imaging data accounts for about 90% of all healthcare data1 and, until... Read more

Industry News

view channel
Image: The acquisition will expand IBA’s medical imaging quality assurance offering (Photo courtesy of Radcal)

IBA Acquires Radcal to Expand Medical Imaging Quality Assurance Offering

Ion Beam Applications S.A. (IBA, Louvain-La-Neuve, Belgium), the global leader in particle accelerator technology and a world-leading provider of dosimetry and quality assurance (QA) solutions, has entered... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.