We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us
GLOBETECH PUBLISHING LLC

Download Mobile App




Nanoparticles Demonstrate Use as Injectable Marker

By MedImaging International staff writers
Posted on 01 Aug 2017
Print article
Image: An illustration of a multifunctional Tantalum oxide/silica core/shell nanoparticles (TSNs) with a radiopaque core for X-ray imaging, conjugated fluorescent dye for fluorescent imaging, a dense core material with a high sound-scattering effect for ultrasound imaging, and a silica surface for adhesive property (Photo courtesy of Nature Communications).
Image: An illustration of a multifunctional Tantalum oxide/silica core/shell nanoparticles (TSNs) with a radiopaque core for X-ray imaging, conjugated fluorescent dye for fluorescent imaging, a dense core material with a high sound-scattering effect for ultrasound imaging, and a silica surface for adhesive property (Photo courtesy of Nature Communications).
Researchers have found a new tissue adhesive that can be detected by clinical imaging modalities, and is also extremely biocompatible for minimally invasive procedures.

The injectable biocompatible radiopaque Tantalum oxide/Silica core/shell Nanoparticles (TSN) were not only very adhesive, but also demonstrated high-contrast for real-time imaging. Adhesives are becoming a convenient alternative to staples and sutures for reconnecting injured tissues and closing wounds following trauma or surgery, especially in minimally invasive procedures.

The results were published online in the July 19, 2017, issue of the journal Nature Communications by the researchers from the Seoul National University (Seoul, South Korea) and other academic and medical institutions in South Korea. The TSN particles cause significantly less inflammation, and cellular toxicity than CyanoAcrylate and Lipiodol (CA-Lp), imageable tissue adhesives.

TSNs could be used for image-guided procedures such as needle biopsy, catheter-directed embolotherapy, percutaneous angioplasty, vertebroplasty and Radio Frequency (RF) / microwave ablation. These minimally invasive procedures are increasingly used to replacing conventional surgery to control internal bleeding, to perform organ biopsies, and for vessel occlusion for example.

The researchers were able to demonstrate that the TSN glue was clearly visualized by X-Ray fluoroscopy, Computed Tomography (CT), Magnetic Resonance Imaging (MRI), ultrasound, and other clinical modalities. Tantalum oxide is inert, takes time to biodegrade in the body, and is normally only required in very small quantities in image-guided procedures, and remain in the target area without any extreme severe adverse reactions.

Related Links:
Seoul National University

New
Digital X-Ray Detector Panel
Acuity G4
New
Portable X-ray Unit
AJEX140H
New
Transducer Covers
Surgi Intraoperative Covers
New
Mini C-arm Imaging System
Fluoroscan InSight FD

Print article

Channels

Ultrasound

view channel
Image: The addition of POC ultrasound can enhance first trimester obstetrical care (Photo courtesy of 123RF)

POC Ultrasound Enhances Early Pregnancy Care and Cuts Emergency Visits

A new study has found that implementing point-of-care ultrasounds (POCUS) in clinics to assess the viability and gestational age of pregnancies in the first trimester improved care for pregnant patients... Read more

Nuclear Medicine

view channel
Image: PSMA-PET/CT images of an 85-year-old patient with hormone-sensitive prostate cancer (Photo courtesy of Dr. Adrien Holzgreve)

Advanced Imaging Reveals Hidden Metastases in High-Risk Prostate Cancer Patients

Prostate-specific membrane antigen–portron emission tomography (PSMA-PET) imaging has become an essential tool in transforming the way prostate cancer is staged. Using small amounts of radioactive “tracers,”... Read more

Imaging IT

view channel
Image: The new Medical Imaging Suite makes healthcare imaging data more accessible, interoperable and useful (Photo courtesy of Google Cloud)

New Google Cloud Medical Imaging Suite Makes Imaging Healthcare Data More Accessible

Medical imaging is a critical tool used to diagnose patients, and there are billions of medical images scanned globally each year. Imaging data accounts for about 90% of all healthcare data1 and, until... Read more
Copyright © 2000-2025 Globetech Media. All rights reserved.