We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us
GLOBETECH PUBLISHING LLC

Download Mobile App




IR Imaging Technology Advances Cancer Diagnosis

By MedImaging International staff writers
Posted on 29 Jul 2019
Print article
Image: WPS imaging of an ovarian cancer cell (a), lipids (b), proteins (c), and off-resonance (d) respectively (Photo courtesy of Ji-Xin Cheng et al).
Image: WPS imaging of an ovarian cancer cell (a), lipids (b), proteins (c), and off-resonance (d) respectively (Photo courtesy of Ji-Xin Cheng et al).
A new study shows how a widefield photothermal sensing (WPS) microscope can provide ultrafast chemical infrared (IR) imaging of biological and material specimens.

Developed by the Chinese Academy of Sciences (Shenyang, China), Purdue University (Lafayette, IN, USA), Boston University (MA, USA), and other institutions, the new method allows examination of living cancer cells, rather than desiccated samples, as required by traditional IR spectroscopy. The WPS microscope is based on photothermal detection of differences between the between the hot and cold states of a tissue, achieved by shining both an IR excitation laser and a visible pulsed blue light-emitting diode (LED) probe laser through a sample.

To enable high-throughput detection of IR absorption, the researchers developed a virtual lock-in camera, with the exposure frames synchronized to the probe pulses and the IR pulses at the same repetition rate, with precisely controlled time delays. The lock-in camera enables chemical imaging at speeds of up to 1,250 frames per second, with high spectral fidelity and a spatial resolution one order of magnitude higher than that of traditional IR microscopy. WPS microscopy can thus open a new way for high-throughput characterization of biological and material specimens. The study was published on July 19, 2019, in Science Advances.

“Current medial practice is to spend one to two days to culture a specimen, then a doctor can tell you if you if you have an infection or not. But if we can measure that at a single bacterium level, that's a rapid detection. That will be a very important application of this platform,” said senior author Ji-Xin Cheng, phD, of Boston University. “This new method would allow the detection of aggressive breast, prostate, and other cancers with biomarker information and at submicron spatial resolution.”

Photothermal sensing techniques are widely used in material science, and are particularly useful for noninvasive inspection of thin film coatings.

Related Links:
Chinese Academy of Sciences
Purdue University
Boston University

New
Digital Radiography System
DigiEye 330
Mobile Barrier
Tilted Mobile Leaded Barrier
New
MRI System
Ingenia Prodiva 1.5T CS
Ultrasound Scanner
TBP-5533

Print article

Channels

Ultrasound

view channel
Image: The addition of POC ultrasound can enhance first trimester obstetrical care (Photo courtesy of 123RF)

POC Ultrasound Enhances Early Pregnancy Care and Cuts Emergency Visits

A new study has found that implementing point-of-care ultrasounds (POCUS) in clinics to assess the viability and gestational age of pregnancies in the first trimester improved care for pregnant patients... Read more

Nuclear Medicine

view channel
Image: PSMA-PET/CT images of an 85-year-old patient with hormone-sensitive prostate cancer (Photo courtesy of Dr. Adrien Holzgreve)

Advanced Imaging Reveals Hidden Metastases in High-Risk Prostate Cancer Patients

Prostate-specific membrane antigen–portron emission tomography (PSMA-PET) imaging has become an essential tool in transforming the way prostate cancer is staged. Using small amounts of radioactive “tracers,”... Read more

Imaging IT

view channel
Image: The new Medical Imaging Suite makes healthcare imaging data more accessible, interoperable and useful (Photo courtesy of Google Cloud)

New Google Cloud Medical Imaging Suite Makes Imaging Healthcare Data More Accessible

Medical imaging is a critical tool used to diagnose patients, and there are billions of medical images scanned globally each year. Imaging data accounts for about 90% of all healthcare data1 and, until... Read more
Copyright © 2000-2025 Globetech Media. All rights reserved.